不同异嗜性粒细胞与淋巴细胞比值雏鸡对肠炎沙门菌抗性差异的分析

doi:10.11843/j.issn.0366-6964.2017.08.018

Abstract

Abstract:

This study was conducted to reveal the difference of immune response upon Salmonella enteritidis (SE) infection between chickens with different Heterophil and Lymphocyte ratio, and trying to prove that chicken flocks of low H/L values has better resistance to Salmonella. Chicken with high and low H/L ratio were selected as parents, and the offspring were divided as High H/L Group and Low H/L Group (HG and LG). The ratio of male and female is 1:3. The chicks were challenged with SE at 7 days old. Liver, cecum and blood serum were collected at 1, 2, 4, 7 and 13 dpi (days post infection). Our results showed that the mortality rate of LG (16.7%) was significantly lower than HG (22.9%). The CFU of SE in liver were significantly different between HG and LG (P<0.05) at 1, 2, 4 and 7 dpi. IL-6 in serum were remarkably higher in Low H/L group than in high group (P<0.05) at 1, 2 and 4 dpi. Low H/L chickens had more TNF-α and LTB-4 in serum than high H/L chickens (P<0.05) at 1, 2 dpi. Chicken with low H/L ratio might have stronger immune response against bacterial infection.

CLC Number:

S813.2

YING Fan, LI Peng, XING Si-yuan, LI Qing-he, ZHENG Mai-qing, LIU Ran-ran, CUI Huan-xian, WEN Jie, MA You-ji, ZHAO Gui-ping. The Analysis of the Difference of Salmonella Resistance between High and Low Heterophil/Lymphocyte Ratio in Chickens[J]. ACTA VETERINARIA ET ZOOTECHNICA SINICA, 2017, 48(8): 1529-1534.

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References

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The Analysis of the Difference of Salmonella Resistance between High and Low Heterophil/Lymphocyte Ratio in Chickens

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